Rachel McAdams
An iconic role like Regina George would define the career of numerous actresses. It was just the beginning of a fantastic career for Rachel McAdams. McAdams has appeared in films and television series such as The Notebook, Wedding Crashers, Red Eye, The Family Stone, State of Play, The Time Traveler’s Wife, Sherlock Holmes and its sequel, Morning Glory, Midnight in Paris, The Vow, About Time, True Detective, Spotlight, Doctor Strange and its 2022 sequel, Disobedience, Game Night, and Eurovision Song Contest: The Story of Fire Saga since her 2004 role in Mean Girls.
Amanda Seyfried
Amanda Seyfried, like Rachel McAdams, rose to prominence in Mean Girls and has subsequently had a varied and successful career. She starred in Mamma Mia! and its sequel Mamma Mia! Here We Go Again, Jennifer’s Body, Dear John, Letters to Juliet, Red Riding Hood, In Time, Les Misérables, A Million Ways to Die in the West, Ted 2, First Reformed, and Mank. Her greatest triumph came in 2022, when she received the Primetime Emmy Award for Best Lead Actress in a Limited or Anthology Series or Movie for her role as Elizabeth Holmes in The Dropout.